LigoCyte's technical focus is directed at understanding and controlling cellular interactions governed by the binding of molecules on the surface of a cell with complementary molecules on another cell. Cell communication and interactions are vital to inflammation, healing of wounds, embryonic growth, the spread and growth of tumor cells and the entry and dissemination of microbes in the body.

Bioadhesion is the process used to recruit leukocytes in response to inflammatory events and infections. The recruiting process involves many complex biochemical interactions. LigoCyte's areas of focus include selectins, integrins, chemokines and cytokines. Selectins are the bioadhesion molecules responsible for causing leukocytes (white blood cells) to slow and roll along the walls of blood vessels. The slowing and rolling is followed by the integrin-mediated sticking to the vessel wall and then passing through the wall to the site of inflammation or infection.

In infectious disease, a pathogenic microorganism trafficks from its point of entry to a target tissue similar to how leukocytes move through recognition of cellular addresses and passage through vessel linings. LigoCyte's discovery process has revealed that infections occur because a pathogen has learned to use many of the same molecules in the host's communication network to reach specific tissues and organs. Consequently, any synthetic compound or biological material that blocks or prevents the pathogen's use of the host's adhesion molecules for trafficking has the potential to serve as a therapeutic compound.